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Thymidine

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Description

Thymidine (dT) or pyrimidine deoxyriboside (deoxynucleoside) is a pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose which is used to synthesize DNA and the T-loop of transfer RNA upon sequential phosphorylation to deoxythymidine triphosphate (dTTP). As a constituent of DNA, thymidine pairs with deoxyadenosine (A) in the structure of double-stranded DNA.

Thymidine kinase (TK, EC 2.7.1.21) is an enzyme that catalyses the phosphorylation of deoxythymidine to deoxythymidine monophosphate with a phosphate derived from ATP. Hence, dT may be used to study the distribution, specificity and kinetics of a family of thymidine kinase(s). It derives from a thymine and has a role as a metabolite (human metabolite, Escherichia coli metabolite and mouse metabolite). It is also used as a synchronizer of the cells in S phase of mitosis.

 

Product Specifications:

Catalog Number: ZXB-06-161

CAS Number: 50-89-5

Synonyms: deoxythymidine, 2′-Deoxythymidine

Formula: C10H14N2O5

Molecular Weight: 242.23

Purity: >99%

Storage: 4°C

PubChem Chemical ID: 5789

SDS  |  CoA

Additional information

CatalogID

ZXB-06-161-1, ZXB-06-161-10, ZXB-06-161-25, ZXB-06-161-5