ZX-44112-96 | Hemoglobin-Whole Blood & RBCs Assay (Colorimetric)
Hemoglobin (Hb) is an erythrocyte protein complex comprised of two sets of identical pairs of subunits, each of which bind an iron-prophyrin group commonly called heme. Generally containing two alpha or alpha-like globulin chains, the remaining subunits may be beta, gamma, delta or epsilon, or in the case of infants, fetal hemoglobin that is replaced during the first year of life. Heme binds and releases oxygen or carbon dioxide in response to slight changes in local gas tension. Free oxygen or carbon dioxide bound by one heme group facilitates subsequent binding by the other heme groups in a given hemoglobin molecule. Subtle changes in pH also regulate hemoglobin affinity for free gases, resulting in a high level of hemostatic control. Hemoglobin values are associated with a variety of conditions ranging from anemias (low Hb), polycythaemia (high Hb), thalassemia (aberrant chain synthesis), and sickling disorders (abnormal complex shape).
The ZellX® Hemoglobin Detection kit is designed to quantitatively measure all forms of hemoglobin present in blood and RBCs. The kit uses a single reaction solution that is light stable at 4°C and does not contain dangerous chemicals. All forms of hemoglobin are rapidly converted to a single stable form that is measured photometrically. Many samples can be measured without dilution in this safe, simple assay. To measure hemoglobin level in serum and plasma, use our Hemoglobin-Serum & Plasma Assay (Colorimetric) (Cat. No. ZX-44113-96)
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