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Viral RNA Extraction
ZX-44115-96 | Ceruloplasmin (Cp) Colorimetric Assay kit

Ceruloplasmin (Cp) belongs to the family of multicopper oxidases, which are among the few enzymes able to bind molecular oxygen to perform its complete reduction to water. Ceruloplasminm literally meaning ‘a blue substance from plasma’, is a blue copper‐binding (6-7 atoms per molecule) glycoprotein from the a2-globulin fraction of human serum possessing oxidase activity towards aromatic diamines and catechol. The Ceruloplasmin found in the serum is mainly produced in liver, but it is also expressed in brain, lung, spleen and testis. Ceruloplasmin contains 95% of the copper in serum, is involved in the safe handling of oxygen in several metabolic pathways in vertebrates, and is associated with reproduction. Specialized copper sites have been recruited during evolution to provide long-range electron transfer reactivity and oxygen binding and activation in proteins destined to cope with oxygen reactivity in different organisms.

Aceruloplasminaemia is an autosomal recessive disorder of iron metabolism characterized by the complete absence of Ceruloplasmin. Due to the essential role of Ceruloplasmin in iron metabolism, aceruloplasminaemic patients suffer from iron overload in tissues, and subsequent clinical complications including diabetes, retinal degeneration and neurodegeneration.

The ZellX® Ceruloplasmin Activity Kit has been designed to quantitatively measure Ceruloplasmin activity in diluted serum and urine samples. The Ceruloplasmin in the standards and samples reacts with the substrate to produce a fuchsia-colored (pink-purple) product. The optical density is read at 560 nm. Increasing levels of Ceruloplasmin in the samples results in an increase in the density of the colored product.

Viral RNA Extraction
Species independent
Use: Measure Ceruloplasmin Activity in one hour
Sample: Serum & Urine
Sample/Kit:  41 in Duplicate
Sensitivity: 3.26 mU/mL
Stability: -20°C
Cat No. ZX-44115-96
Size 96 wells
Price 328.00 €
Ordering: You can also order using info[at]zellx.de or FAX at +49(0)30 81309086

Technical Support: Customer satisfaction is very important to us. Please call us at +49(0)30 81309085 or send an email to technical[at]zellx.de with your technical questions. A member of our scientific staff will be glad to assist you.