Corticosterone (C₂₁H₃₀O₄4, Kendall’s Compound ‘B’) is a glucocorticoid secreted by the cortex of the adrenal gland. Corticosterone is secreted in response to stimulation of the adrenal cortex by Adrenocorticotropic hormone (ACTH), and is the precursor of aldosterone. Corticosterone is a major indicator of stress in nonhuman mammals. Studies have shown a link between corticosterone‐mediated increased level of stress and impairment of long term memory retrieval, as well as chronic corticosterone elevation due to dietary restrictions and in response to burn injuries. In addition to stress levels, corticosterone is assumed to play a decisive role in sleep-wake patterns. The ZellX® Corticosterone CLIA kit is designed to quantitatively measure Corticosterone present in serum, plasma, urine, extracted dried fecal samples, and tissue culture media samples. For analyzing corticosterone using colorimetric ELISA method use either our corticosterone ELISA Kit Cat. No. ZX-55101-96 or high sensitivity corticosterone ELISA Kit Cat. No. ZX-55110-96