Rapamycin, also known as sirolimus is a macrolide antibiotic isolated from Streptomyces hygroscopicus with anti-fungal, anti-inflammantory, anti-tumor, and immunosuppressive properties. It inhibits the protein, mechanistic target of rapamycin (mTOR), which is a key regulatory kinase in controlling the cytokine-mediated cellular proliferation. Additionally, Rapamycin induces apoptosis and inhibits angiogenesis and proliferation in tumor cell lines.
Catalog Number: ZXB-03-117
CAS Number: 53123-88-9
Synonyms: 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine; AY 22989; Sirolimus
Molecular Weight: 914.17
PubChem Chemical ID: 5284616